Agnoletti Fabrizio

Fabrizio Agnoletti | Istituto Zooprofilattico Sperimentale delle Venezie Role Director
Structure Department of Animal Pathology and Public Health
SCT4 – Friuli Venezia Giulia
Phone +39 0432 561529 (Udine)
+39 0434 41405 (Pordenone)

Professional profile

Fabrizio Agnoletti is Director of the SCT4 – Friuli Venezia Giulia of the Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe) since 2020. From 2003 to 2019 he was Director of the SCT2 – Treviso, Belluno and Venezia of the IZSVe. Since december 2020 he is also Director of the Animal Pathology and Public Health Department of the IZSVe.

He graduated in Veterinary Medicine (University of Bologna), with a postgraduate specialization in Veterinary Public Health (University of Milan), the post-graduate diploma of the Scientific Research School of the Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna (Brescia, Italy) and a Master’s in Public Administration Management  (CUOA Foundation, Altavilla Vicentina, Vicenza, Italy).

He is skilled in microbiology and diagnosis of animal infectious diseases, with a specific interest in laboratory phenotypic (including mass spectrometry) and molecular (PCRs, MLST, PFGE, ribotyping) methods to identify and characterize microorganisms of veterinary interest, including antimicrobial resistant/multi-resistant bacteria. He is an expert in rabbit diseases. His research interests are in the laboratory diagnosis of infectious diseases of rabbits and molecular characterization of bacteria, with special skills in Clostridium difficile and Staphylococcus aureus (MRSA), evaluation and molecular characterization of antimicrobial resistance and the application of mass spectrometry to bacteriology.

He is the scientific director of various projects funded by pharmaceutical companies for the evaluation of the in vitro efficacy of molecules with antimicrobial action against bacterial pathogens in the rabbit. He has been scientific director of numerous research projects, oriented, in the last five years, to the study of zoonotic bacteria (Listeria monocytogenes and Clostridium difficile) and multiresistant (MRSA, ESBL-producing E. coli, Acinetobacter baumanni, Pseudomonas aeruginosa and Klebsiella pneumoniae) in numerous animal species.

He is author or co-author of over 200 scientific publications and communications.


  • Tomao P., Pirolo M., Agnoletti F., Pantosti A., Battisti A., Di Martino G., Visaggio D., Monaco M., Franco A., Pimentel de Araujo F., Palei M., Benini N., Motta C., Bovo C., Di Renzi S., Vonesch N., Visca P., (2020).  Molecular epidemiology of methicillin-resistant Staphylococcus aureus from dairy farms in North-eastern Italy. International Journal of Food Microbiology, 6;332:108817. doi: 10.1016/j.ijfoodmicro.2020.108817. Online ahead of print.PMID: 32777624
  • Rosa N.M., Agnoletti F., Lollai S., Tola S. , (2019). Comparison of PCR-RFLP, API® 20 Strep and MALDI-TOF MS for identification of Streptococcus spp. collected from sheep and goat milk samples. Small Ruminants Research 180 (2019), 35-40.
  • Barberio A., Mazzolini E., Dall’Ava B., Rosa G., Brunetta R., Zandonà L., Drigo I., Moschioni C., Guolo A., Bonamico S., Busa A., Segalin C.,  Biasio L., Moroni P., Agnoletti F., (2019). A longitudinal case study on the dissemination of ST398 methicillin-resistant Staphylococcus aureus within a dairy cow herd. Foodborne Pathogens and Diseases. Published Online: 4 Nov 2019
  • Agnoletti F., Arcangeli G., Barbanti F., Barco L., Brunetta R., Cocchi M., Conedera G., D’Este L., Drigo I., Spigaglia P., Mazzolini E., (2019). Survey, characterization and antimicrobial susceptibility of Clostridium difficile from marine bivalve shellfish of North Adriatic Sea Int. J.  Food Microbiol. 298,74-80. (doi: 10.1016/j.ijfoodmicro.2019.03.003)
  • Agnoletti F., Brunetta R., Bano L., Drigo I., Mazzolini E. (2018). Longitudinal study on antimicrobial consumption and resistance in rabbit farming. Int J Antimicrob Agents. 2018 Feb;51(2):197-205. doi: 10.1016/j.ijantimicag.2017.10.007. Epub 2017 Oct 27. PMID:29111433
  • Drigo I., Mazzolini E., Bacchin C., Tonon E., Puiatti C., Bano L., Spigaglia P., Barbanti F., Agnoletti F., (2015). Molecular characterization and antimicrobial susceptibility of Clostridium difficile  isolated from rabbits raised for meat production. Vet Mic.181, 303-307.
  • Spigaglia P., Drigo I., Barbanti F., Mastrantonio P., Bano L., Bacchin C., Puiatti C., Tonon E., Berto G., Agnoletti F. (2014) Characterization of Clostridium difficile strains isolated from swine and dogs in Italy. Anaerobe. 2014 Oct 12. pii: S1075-9964(14)00146-2. doi: 10.1016/j.anaerobe.2014.10.003. [Epub ahead of print]
  • Agnoletti F., Mazzolini E., Bacchin C., Bano L., Berto G., Rigoli R., Muffato G., Coato P., Tonon E., Drigo I. (2014). First reporting of Methicillin-Resistant Staphylococcus aureus (MRSA) ST398 in an industrial rabbit holding and in farm-related people.Veterinary Microbiology 170, 172-177
  • Gallina G., Lucatello L., Drigo I., Cocchi M., Scandurra S., Agnoletti F., Montesissa C. (2010). Kinetics and intrapulmonary disposition of tilmicosin after single repetaed oral bolus administration to rabbits. Vet.Res. Commun., 34, S69-S72
  • Agnoletti F., Ferro T., Guolo A., Marcon B., Cocchi M., Drigo I., Mazzolini E., Bano L. (2009). A survey of Clostridium spiroforme antimicrobial susceptibility in rabbit breeding. Vet. Microbiol. 136, 188-191.