Ceglie Letizia

Letizia Ceglie | Istituto Zooprofilattico Sperimentale delle Venezie Role Biologist
Department SCT3 – Padova and Rovigo. Diagnostics in Animal Health
Phone +39 049 8084237
E-mail lceglie@izsvenezie.it

Professional profile

Letizia Ceglie graduated in Biological sciences and obtained a postgraduate diploma in Microbiology and human virology at the University of Bologna in 2000 and a Master’s Degree in Biotechnology at the University of Urbino (FanoAteneo) in 2002 and a second Level Master’s Degree in Forensic Veterinary Science in 2020. In 1995 she joined the Istituto Zooprofilattico delle Venezie (IZSVe) as a young researcher and during the last 20 years or so, her main interests have been in molecular and cellular biology, prevalently in the fields of human and animal health, laboratory diagnostics (mainly development and standardization of diagnostic tests) and animal disease surveillance.

She participate in COST Action 855 on Animal Chlamydioses and Zoonotic implications, European Union 6th Framework Programme. She was esearcher in a European Union funded research project on the application of innovative methods for the diagnosis of viral diseases of equines, such as viral arteritis, rhino-pneumonitis virus, influenza (1995- 1999). She also participated in national research projects concerning zoonoses and animal health, specifically on BVD, IBR, Neosporosis, SBV, Q Fever, Leptospirosis, Hepatitis E virus, PRRSV; the main focus of this researches was on disease monitoring after experimental infection, evaluation of the performance of the diagnostic tools applied in the diagnosis, and the application of innovative typing methods (MLVA , microarray) to characterize the collected strains. She has also been research project coordinator in the field of chlamydial infections (Animal chlamydiosis and zoonotic implications) and BVD type 3 infection.

At present she is involved in research projects on new strains of BVDV and some zoonotic agents as HEV, Leptospira, Coxiella burnetii, Erysipelothrix rhusiopathiae. Her activities also include the organization of proficiency tests for etiological diagnosis of pathogens affecting bovines and swine.

Publications

  • Birch-Machin I., Ryder S., Iniguez P., Koptopoulos G., Marault M., Ceglie L., Zientara S., Mumford J., Binns M., Crucière C., Cancellotti F.M., Davis-Poynter N. and Hannant D. (2000) “Utilisation of bacteriophage display libraries to identify peptide sequences recognised by Equine Herpesvirus type 1 specific sera.” Journal of Virological Methods 88, pp.89-104.
  • Ceglie L., Lafisca S., Guadagno C., Dalla Pozza G., Capello K., Bano L.,Vicari N., Donati M., Mion M., Giurisato I., Lombardo D., Pozzato N., Cevenini R., and Natale A. (2007) Serological surveillance in North-Eastern Italy for the presence of Chlamydophyla spp from birds and molecular characterisation of PCR isolates within the area of Venice. COST Action 855 Animal Chlamydiosis and its zoonotic implications Proceedings . Pulawy, 10-11 September 2007, (full- length paper pp. 62-67).
  • Natale A., Busani L., Comin A., S. De Rui, L. Buffon, S. Nardelli, S. Marangon, L. Ceglie (2009) First report of bovine Q-fever in north-eastern Italy: preliminary results. Clinical Microbiology and Infection April 30. 15 (Suppl.2) : 144-145.
  • Donati M., Laroucau K., Storni E., Mazzeo C., Magnino S. , Di Francesco A., Baldelli R., Ceglie L. , Renzi M. and Cevenini R. (2009) Serological response to pgp3 protein in animal and human chlamydial infections Veterinary Microbiology vol.135 pp.181-185.
  • Mutinelli F., Schiavon E., Ceglie L., Fasolato M., Natale A., Rampin F., Carminato A. (2011) Bovine besnoitiosis in imported cattle in Italy. Vet.Parasitol. (175).
  • Natale A., Bucci G., Capello K., Barberio A., Tavella A., Nardelli S., Marangon S., Ceglie L. (2012) Old and new diagnostic approaches for Q fever diagnosis: correlation among serological (CFT, ELISA) and molecular analyses. Comp.Immunol.Microbiol.Infect.Dis. 35(4):375-379.
  • Ceglie L., Monaco F., Bonci M., Calistri P., Bano L., Goffredo M., Belfanti I., Pinoni C., Polci A., Nardelli S., Bonfanti L., Marangon S., Lelli R. (2012). First report of Schmallenberg virus in Italy. Abstracts – 6th Annual Meeting EPIZONE “Viruses on the Move”, Brighton. Abstracts – 6th Annuale Meeting EPIZONE “Viruses on the move”.
  • Drigo M., G. Franzo, I. Belfanti, M. Martini, A. Mondin, L. Ceglie (2014) Validation and comparison of different end point and real time RT-PCR assays for detection and genotyping of porcine reproductive and respiratory syndrome virus J Virol Methods. Jun 15;201:79-85.
  • Drigo M., Franzo G., Gigli A., Martini M., Mondin A., Gracieux P., Ceglie L. (2014) The impact of porcine reproductive and respiratory syndrome virus genetic heterogeneity on molecular assay performances. J Virol Methods. Jun 15;202:79-86.
  • Monne I., L. Ceglie, G. Di Martino*, A. Natale, S. Zamprogna, A. Morreale, E. Rampazzo, G. Cattoli and L. Bonfanti (2014) Hepatitis E virus genotype 4 in a pig farm, Italy, 2013 Epidemiol. Infect., Page 1-5.
  • Giammarioli M., Ceglie L., Rossi E., Bazzucchi M., Casciari C., Petrini S., De Mia GM (2015) Increased genetic diversity of BVDV-1: recent findings and implications thereof. Virus Genes Feb;50:147-51.
  • Ceglie L., Guerrini E., Rampazzo E., Barberio A., Tilburg J.J., Hagen F., Lucchese L., Zuliani F., Marangon S., Natale A. (2015) Molecular characterization by MLVA of Coxiella burnetii strains infecting dairy cows and goats of north-eastern Italy. Microbes Infect. 17(11-12):776-781.
  • Ceglie L., Natale A., Guerrini E., Terregino C., Mion M., Marchione S., Trovò G., Granato A., Catania S. (2015) First description and isolation of the new species Chlamydia gallinaceae from Italian commercial hens with respiratory signs and conjuctivitis. In: EMAC 3 – Proceedings of the Third European Meeting on Animal Chlamydiosis and Zoonotic Aspects. Anses, Maisons-Alfort, France, September 24-25, 2015, 21-22.
  • Lucchese L., Capello K., Barberio A., Zuliani F., Stegeman A., Ceglie L., Guerrini E., Marangon S., Natale A. (2015) IFAT and ELISA phase I/phase II as tools for the identification of Q fever chronic milk shedders in cattle. Microbiol. 179(1-2):102-108.
  • Natale A., Ceglie L., Lucchese L., Zuliani F., Marangon S., Barberio A. (2017) Diagnostic Approach to Coxiella burnetii infection in animals. In: João Carlos Caetano Simões, Sofia Ferreira Anastácio, Gabriela Jorge Da Silva (eds). The principle and practice of Q fever. The one health paradigm. 7, New York, Nova Science Publishers, p. 107-134.
  • Barberio A., Ceglie L., Lucchese L., Zuliani F., Marangon S., Natale A., (2017) Epidemiology of Q fever in cattle. In: João Carlos Caetano Simões, Sofia Ferreira Anastácio, Gabriela Jorge Da Silva (eds). The principle and practice of Q fever. The one health paradigm. 11, New York, Nova Science Publishers, p. 189-212.
  • Bazzucchi M., Bertolotti L., Ceglie L., Giammarioli M., Rossi E., Rosati S., De Mia G.M. (2017) Complete nucleotide sequence of a novel bovine viral diarrhea virus subtype 1 isolate from Italy. Arch.Virol. 162(11):3545-3548.
  • De Sabato L., Lemey P., Vrancken B., Bonfanti L., Ceglie L., Vaccari G., Di Bartolo I. (2018) Proposal for a new subtype of the zoonotic genotype 3 Hepatitis E virus: HEV-3l. Virus Res. 248:1-4.
  • Ceglie L., Rampazzo E., Perin R., March A., Aschbacher R., Lorenzi G., Pagani E., Trevisiol K., Corrò M. (2018) Molecular characterization of MRSA isolates from staff members and inpatients of an Italian long-term care facility. In: Annual Conference 2018 Poster Abstract Book Microbiology Society. Birmingham,UK, 10-13 April 2018, 284.
  • Bellinati L., Ceglie L., Natale A., Zuliani F., Monne I., Schivo A., Zecchin B., Bonfanti L., Amato L., Cunial G., Obber F., Bregoli M., C. Citterio (2018) Detection and genotyping of hepatitis E virus in wild ungulates from North-Eastern Italy In: ESVV Abstract Book p.31.
  • Belfanti I., Decaro N., Lucente M.S., Buonavoglia C., Giammarioli M., Lucchese L., Cecchinato M., Martini M., Schiavo M., Lora M., Ceglie L. and Nardelli S. (2018) Does vaccination of pregnant cows against bovine viral diarrhea viruses confer foetal protection against HoBi-like pestivirus infection? In: ESVV Abstract Book p.48.
  • Zecchin B., Schivo A., Milani A., Fusaro A., Zamperin G., Bellinati L., Ceglie L., Natale A., Bonfanti L., Cunial G., Obber F., Di Bartolo I., Citterio C., Monne I. (2019) Identification of a zoonotic genotype 3 hepatitis E subtype in wildlife in north-eastern Italy. Infect.Genet.Evol. 71:16-20.
  • Menandro M.L., Dotto G., Mondin A., Martini M., Ceglie L., Pasotto D. (2019) Prevalence and characterization of methicillin-resistant Staphylococcus pseudintermedius from symptomatic companion animals in Northern Italy: Clonal diversity and novel sequence types. Comp. Immunol. Microbiol. Infect.Dis. 66:101331.
  • Regidor-Cerrillo J., Horcajo P., Ceglie L., Schiavon E., Ortega-Mora L.M., Natale A. (2020) Genetic characterization of Neospora caninum from Northern Italian cattle reveals high diversity in European N. caninum populations. Res. 119:1353-1362.
  • Bertasio C., Boniotti M.B., Lucchese L., Ceglie L., Bellinati L., Mazzucato M., Furlanello T., D’Incau M., Natale A. (2020) Detection of New Leptospira Genotypes Infecting Symptomatic Dogs: Is a New Vaccine Formulation Needed? Pathogens 9(6):484-484.